In a zombie-infested world, El Santos, an overweight pacheco fighter, has recently divorced La Tetona Mendoza, a voluptuous, wild female wrestler. To get out of his depression, Santos begins a campaign to help Sahuayo's zombie population. However, his philanthropy soon becomes a wild, profitable ride that causes an accidental genocide of zombies, causing Mexico's economy to bankrupt and for his ex-wife to assume the presidential title. In a country ruled by women, Santos must stop his wife and her female-dominated empire, and restore the zombies to the streets of Mexico.