Bidding goodbye to his fiancée, Evelyn Haselton, Harry Littlejohn goes West to seek his fortune, where he contracts pneumonia and almost dies. Dr. Jim nurses Harry back to health and the two men become fast friends. Later, the doctor travels to the East to visit a dying friend, falls in love with the ailing man's daughter and marries her. When the newlyweds return home, Harry is shocked to see that his friend's new wife is Evelyn, but respect for the doctor prevents him from revealing their former relationship. Because Doctor Jim's work keeps him away from home so frequently, Evelyn imagines he no longer loves her and agrees to elope with Jack Monroe. Harry discovers their plans and shoots Jack but is mortally wounded in the struggle.